This is one of the most common questions I get asked, and I always direct the answer to the clinical study. I have included a summary along with the entire study in the pdf viewer below.
Summary of Study
CholesLo shows clinical significance in helping reduce plasma cholesterol and homocysteine levels and therefore affects favorably the risk of subsequent development of cardiovascular disease. Furthermore, our findings suggest that the dose required to cause such improvements in plasma lipid profile is safe enough to be considered for use in general population.