đź’Š Selegiline – Doctor Gives Do’s & Don’ts For 2024

A little while ago, I wrote an article entitled, Refractory Period – How To Have More Orgasms, Better Sex & Fix “ED”.

In the video, I mentioned a drug called Selegiline, also known as L-Deprenyl or Eldepryl.

I stated that this is a drug I’ve used on and off for over 20 years.

I didn’t say much about it, but I asked my subscribers if they wanted more details about Selegiline, to let me know in the comments section.

Well, I got a bunch of people asking questions and that’s what today’s topic is going to be about – Selegiline:

  • What is it?
  • How does it work?
  • What are the benefits?
  • What is it prescribed for?
  • How to use it correctly – for sex drive, better mood, brain health, longevity, and so forth.
  • The best dosages, timing, etc.
  • Lastly, potential warnings.

And before I start, I need to give a polite legal disclaimer: Please don’t do anything unless you speak to your doctor first. This is for entertainment purposes only.

What Is Selegiline?

It’s a medication called monoamine oxidase type B (MAO-B) inhibitor. This is an enzyme which sucks up the dopamine that is not being used by your brain.

By inhibiting this MAO-B enzyme, there’s more dopamine available for your brain to use.


This is why they prescribe such drugs to Parkinson’s patients because they lack dopamine production and sensitivity to dopamine.

Thus, Selegiline is one such drug prescribed to Parkinson’s patients, usually combined with levodopa…. Which is a precursor to dopamine.

This means that your body can now hopefully produce MORE dopamine and ALSO better use of the dopamine that’s available. This is a double benefit.

Dopamine Side Note:

And for those of you who don’t know, dopamine is a neurotransmitter made in your brain. Some also categorize it as a hormone.

Some call Dopamine the “pleasure” chemical because it’s associated with sex, gambling, porn, eating and similar events.

Dopamine plays a role as a “reward center” … and in many body functions, including memory, muscle movement, motivation, mood, attention, and more.

High or low dopamine levels are associated with diseases including Parkinson’s disease, restless legs syndrome, and attention deficit hyperactivity disorder (ADHD).

How Does Selegiline Relate to Better Sex Drive?

Okay, so now you know what it is, how it works, what it’s prescribed for, and some of the benefits.

But, how does all of this relate to a better sex drive, having more orgasms, improved mood, neuroprotective and brain health, increased motivation, and could be one of the most potent and safest anti-aging drugs?…

Well, let me first share a quick story with you related to my usage of Selegiline.

It was in my early 20s and a bodybuilding friend of mine was telling me about all the biohacking stuff he was using to improve his body.

Yes, steroids were one of them – but also brain stuff such as nootropics.

This was 30 years ago, way ahead of all the proclaimed biohacking experts.

I started using a bunch of stuff and he suggested Selegiline to keep me focused in school. I always had a hard time paying attention in class…since I was thinking about going to the gym, making money, and of course, girls!

Anyway, I noticed my memory, attention, motivation, and mood all improved.

Over time though, I stopped taking some of these substances and Selegiline was one of them. I think I had a hard time getting it.

Anyway, about 10 years later, I read in one of the life extension magazines about Selegiline and how it’s one of the most anti-aging, and neuroprotective brain health drugs… that’s also safe.

This was also about the same time my aunt was diagnosed with Parkinson’s.

So, I started taking it for all the benefits I mentioned, PLUS to help reduce my own risk of getting Parkinson’s.

Dopamine Over Production & Refractory Period

This is especially important these days because so many people are overstimulated due to the internet and mobile phones that they are OVER producing dopamine, which could mean less production later in life and at the same time, less sensitivity to it NOW.


Now, when you don’t produce as much dopamine, prolactin levels can go up and in men, this means lower sex drive and a decrease in your ability to have more orgasms, more often.

This is where the refractory period comes in.

Before sex, you are “hunting” and “searching” to have intercourse. Your dopamine levels go up. After you orgasm, dopamine drops, and prolactin levels go up.

This creates a calming effect.

Over time, prolactin levels go back down and dopamine levels go back up. And now, you can get an erection again and have an orgasm.

When you’re younger, this “refractory” period is short or shorter. As you age, it gets longer and longer.

When at one time you could have 2-3 orgasms in a day, years later you might have 1 or 2 orgasms a week and eventually maybe just a month or longer.

There are many hormonal reasons for this and of course, dopamine is one of these factors.

But by using selegiline, you can improve dopamine levels and thus, reduce your refractory period, have an erection and orgasm more often, and all the other benefits I mentioned – brain health, better mood, more motivation, longevity, etc., etc.

How And When To Take Selegiline?

Since none of us have Parkinson’s disease, you do NOT take the prescribed dosage, which is typically 5 to 10 mg daily. And Selegiline comes in 5 mg tablets.

The ideal dosage and the one I take is 1 mg daily. Yes, that’s just 10% of the prescribed dosage for Parkinson’s.

Now, I just take a 5 mg tablet and cut it into quarters and that means I take about 1.25 mg daily. So, that’s close enough.


Selegiline’s half-life is about 2-3 hours. It’s fast-acting. So, most of it at this low dose is out of your system in about 4-5 hours.

Keep in mind taking it gives you a little bit of a high. You’re amped up and that’s because a metabolite of it is partially converted to amphetamine.

So, if you’re going to get drug tested, know that it can show positive for amphetamines.

I mention all of this because you obviously don’t want to take it in the evening or before bed, it’s going to cause insomnia.

So, the best time to take it and when I do is first thing in the morning.

Now, if you want to use it for sexual reasons or to feel better and more motivated, then use it about an hour before sex,  going to a party or giving a speech, or some other social event.

Or, where do you get Selegiline? … It’s a prescription drug, so you can ask your doctor. Besides that, I’m sorry… I can’t give you sources. But, you can do your own research.

Natural Alternatives

However, what if you can’t get Selegiline or you don’t want to take a drug? Are there natural alternatives?

Yes, there are lots of things you can do.

For example, Mucuna Pruriens Extract at 25% L-Dopa works like the drug Levodopa and if you recall, it helps replace the missing dopamine in the brain because it’s a precursor to dopamine.

That’s why I included it in AlphaViril, to help promote healthy dopamine levels.

Combined with the testosterone-boosting herbs and other pro-sexual ingredients, AlphaViril will over time, help increase your ability to have sex more often, with better erections and more orgasms.

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